DESCRIPTION
Lenvaxen
Lenvatinib 4 mg & 10 mg
COMPOSITION
LENVAXEN 4 capsules: Each capsule contains Lenvatinib Mesylate INN equivalent to Lenvatinib 4 mg.
LENVAXEN 10 capsules Each capsule conlains Lenvatinib Mesylate INN equivalent to Lenvatinib 10 mg.
INDICATIONS AND USAGE
Lenvatinib is indicated as monotherapy for the treatment of adult patients with progressive, IocaIIy advanced or metastatic, differenliated (papillary/foIIicuIar/Hürthle cell) thyroid carcino- ma (DTC), refractory to radioactiva iodine (RAI). Lenvatinib is indicated as monotherapy for the treatment of adult patients with advanced or unresectable hepatocellular carcinoma (HCC) who have received no prior systemic therapy.
DOSAGE AND ADMINISTRATION
Recommended Dosage for Ditferentiated Thyroid Cancer (DTC)
The recommended dosage of lenvatinib is 24 mg orally once daily until disease progression or until unacceptable toxicity.
Recommended Dosage for Renal Cell Carcinoma (RCC) The recommended dosage of lenvatinib is 18 mg in combina- tion wilh 5 mg everolimus orally once daily until disease progression or until inacceptable toxicity.
Refer to everolimus prescribing information for recommended everolimus dosing intormation.
Manufactured By
Everest Pharmaceuticals Ltd.
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